Detalhe da pesquisa
1.
A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids.
Nat Mater
; 21(1): 110-119, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34518665
2.
Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores - A cautionary disclosure.
Bioorg Med Chem Lett
; 29(4): 560-562, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30616904
3.
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.
Stem Cell Reports
; 18(2): 570-584, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669491
4.
Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy.
Cancer Discov
; 11(10): 2602-2619, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031121
5.
Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis.
Nat Commun
; 12(1): 7336, 2021 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34921158
6.
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.
Cancer Cell
; 39(9): 1227-1244.e20, 2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297917
7.
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides.
J Med Chem
; 61(23): 10767-10792, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30403352
8.
First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib.
ACS Chem Biol
; 11(11): 3179-3190, 2016 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27689388